In a 2006 study published in the American Journal of Epidemiology, Mayo Clinic experts looked at the effects of NSAID medications (like aspirin and ibuprofen) on the urinary health of more than 2,400 white older men. They found that NSAID usage was linked with a lower risk of developing an enlarged prostate, or benign prostatic hyperplasia, a condition known to cause difficulty initiating urination, a weak pee stream, frequent nighttime urination, and more.
“The typical scenario with benign prostatic hyperplasia is that men start getting up three to five times a night to urinate, and their wives ultimately force them to go see a urologist,” study investigator Dr. Michael Lieber stated via Science Daily. Ultimately, the research findings revealed that for men who took NSAIDs, the risk of developing benign prostatic hyperplasia was cut in half compared to those who took a placebo drug. The intervention group was also 35% less likely to experience more extreme urinary symptoms.